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Petr Dzubak Selected Research

Neoplasms (Cancer)

3/2022One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy.
3/20222‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines.
1/2022Cannabidiol-induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET.
4/2018A Synthetic Approach for the Rapid Preparation of BODIPY Conjugates and their use in Imaging of Cellular Drug Uptake and Distribution.
1/2018Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM.
12/2017Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
1/2017Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid.
1/2017Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.
10/2016Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells.
6/2016Biodegradable system for drug delivery of hydrolytically labile azanucleoside drugs.
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Petr Dzubak Research Topics

Disease

18Neoplasms (Cancer)
03/2022 - 08/2002
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2018 - 08/2005
1Melanoma (Melanoma, Malignant)
03/2022
1Hepatocellular Carcinoma (Hepatoma)
03/2022
1Alzheimer Disease (Alzheimer's Disease)
02/2022
1Amyloidosis
04/2018
1Cardiomyopathies (Cardiomyopathy)
04/2018
1Inborn Genetic Diseases (Disease, Hereditary)
01/2018
1Iron Overload
01/2018
1Hemolytic Anemia
01/2018
1Alcoholism (Alcohol Abuse)
12/2017
1Colorectal Neoplasms (Colorectal Cancer)
01/2017
1Breast Neoplasms (Breast Cancer)
08/2016
1Inflammation (Inflammations)
06/2016
1Leukemia
09/2014
1Diamond-Blackfan Anemia (Anemia, Diamond Blackfan)
07/2014
1Asthma (Bronchial Asthma)
05/2009
1Central Nervous System Neoplasms
06/2004
1Glioblastoma (Glioblastoma Multiforme)
06/2004
1Adenocarcinoma of Lung
08/2002
1Carcinoma (Carcinomatosis)
08/2002

Drug/Important Bio-Agent (IBA)

8Pharmaceutical PreparationsIBA
03/2022 - 06/2008
4DNA (Deoxyribonucleic Acid)IBA
03/2022 - 06/2016
4Biomarkers (Surrogate Marker)IBA
01/2022 - 08/2005
4Proteins (Proteins, Gene)FDA Link
11/2012 - 08/2002
3CopperIBA
03/2022 - 12/2017
3Ditiocarb (Sodium Diethyldithiocarbamate)FDA Link
03/2022 - 12/2017
3RNA (Ribonucleic Acid)IBA
03/2022 - 10/2016
3AcidsIBA
01/2018 - 06/2012
2Phosphotransferases (Kinase)IBA
02/2022 - 06/2008
2Disulfiram (Antabuse)FDA Link
01/2022 - 12/2017
2TriterpenesIBA
04/2018 - 01/2017
2HepcidinsIBA
01/2018 - 07/2014
2Aurora KinasesIBA
12/2012 - 06/2008
2bohemineIBA
08/2005 - 08/2002
2Cyclin-Dependent Kinases (cdk Proteins)IBA
08/2005 - 08/2002
1MetalsIBA
03/2022
1Purinergic P1 Receptors (Adenosine Receptor)IBA
03/2022
1tau Proteins (tau Protein)IBA
02/2022
1MetallothioneinIBA
01/2022
1Heavy MetalsIBA
01/2022
1CannabidiolIBA
01/2022
1Atrial Natriuretic Factor (ANF)IBA
04/2018
1Amyloid (Amyloid Fibrils)IBA
04/2018
1Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA
04/2018
1Prealbumin (Transthyretin)IBA
04/2018
1Apolipoprotein A-I (Apolipoprotein A1)IBA
04/2018
1Betulinic AcidIBA
01/2018
1Ferritins (Ferritin)IBA
01/2018
1Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA
01/2018
1IronIBA
01/2018
1Cytostatic AgentsIBA
01/2018
1Transferrin Receptors (Transferrin Receptor)IBA
01/2018
1Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2017
1oleanonic acidIBA
01/2017
1lupaneIBA
10/2016
1Aspartic Acid (Aspartate)FDA Link
08/2016
1Collagen Type I (Type I Collagen)IBA
08/2016
1DecitabineFDA Link
06/2016
1Azacitidine (5 Azacytidine)FDA Link
06/2016
1MethyltransferasesIBA
06/2016
1Antineoplastic Agents (Antineoplastics)IBA
06/2016
1Diclofenac (SR 38)FDA LinkGeneric
06/2016
1Hydroxyl RadicalIBA
01/2015
1dihydrobetulinic acidIBA
01/2015
1ProdrugsIBA
01/2015
1Dexamethasone (Maxidex)FDA LinkGeneric
09/2014
1Prednisolone (Predate)FDA LinkGeneric
09/2014
1GlucocorticoidsIBA
09/2014
1Prednisone (Sone)FDA LinkGeneric
09/2014
1AnthracyclinesIBA
11/2012
1Mitoxantrone (Novantrone)FDA LinkGeneric
11/2012
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2012
1ProteomeIBA
11/2012
1Daunorubicin (Cerubidine)FDA LinkGeneric
11/2012
1Cisplatin (Platino)FDA LinkGeneric
11/2009
1IsotopesIBA
11/2009
1Amino AcidsFDA Link
11/2009
1montelukast (Singulair)FDA Link
05/2009
1LeukotrienesIBA
05/2009
1Adrenal Cortex Hormones (Corticosteroids)IBA
05/2009
1Histones (Histone)IBA
08/2005
1ChromatinIBA
08/2005
1PPAR gammaIBA
06/2004
1ciglitazoneIBA
06/2004
1LigandsIBA
06/2004
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
06/2004

Therapy/Procedure

6Therapeutics
03/2022 - 06/2004
2Drug Therapy (Chemotherapy)
01/2022 - 12/2012
1Aftercare (After-Treatment)
08/2002